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''Ganoderma tsugae'', also known as Hemlock varnish shelf, is a flat polypore mushroom of the genus ''Ganoderma''. In contrast to ''Ganoderma lucidum'', to which it is closely related and which it closely resembles, ''G. tsugae'' tends to grow on conifers, especially hemlocks.〔Kuo, M., MushroomExpert.Com, (''Ganoderma tsugae'' ). (2004, February). Retrieved June 15, 2007.〕 Like ''G. lucidum'', ''G. tsugae'' is said to have medicinal properties.〔Ching-Hua Su1, et al., Taipei Medical University, (Sacchachitin, a Skin Wound Dressing Material from ''Ganoderma tsugae'' ), 2004. Retrieved June 16, 2007.〕 Phylogenetic analysis has begun to better differentiate between many closely related species of ''Ganoderma'';〔Soon Gyu Hong, Hack Sung Jung, (Phylogenetic analysis of ''Ganoderma'' based on nearly complete mitochondrial small-subunit ribosomal DNA sequences ), ''Mycologia'' July/August 2004 vol. 96 no. 4 742–55.〕 however, there is still disagreement as to which have the most medicinal properties. In addition, variations within the same species as well as the growth substrate and environmental conditions all the way through to preparation can have a substantial effect on the medicinal value of the product. Like ''G. lucidum'', ''G. tsugae'' is non-poisonous but generally considered inedible, due to its solid woody nature; however, teas and extracts made from its fruiting bodies allow medicinal use of the compounds it contains. A hot water extraction or tea can be very effective for extracting the polysaccharides; however, an alcohol or alcohol/glycerin extraction method is more effective for the triterpenoids.〔Gary Emberger, Messiah College, (''Ganoderma tsugae'' ), 2006. Retrieved June 16, 2007.〕 Studies in mice has shown that ''G. tsugae'' shows several potential medicinal benefits including anti-tumor activity through some of the active polysaccharides found in ''G. tsugae''〔Mizuno T, Wang G, Zhang J et al: Reishi, Ganoderma lucidum and Ganoderma tsugae: bioactive substances and medicinal effects. Food Rev Intl 1995; 11(1):151-166〕〔Mayuzumi I, Okamoto H & Li J: (Antitumor active protein-containing glycans from the Chinese mushroom songshan lingzhi, Ganoderma tsugae mycelium ). Biosci Biotechnol Biochem 1994; 58(7):1202-1205.〕 ''G. tsugae'' has also been shown to significantly promote wound healing in mice as well as significantly increase the proliferation and migration of fibroblast cells in culture.〔Su CH, Sun CS, Juan SW et al: (Development of fungal mycelia as skin substitutes: effects on wound healing and fibroblast ). Biomaterials 1999; 20(1):61-68.〕 ==References== 〔 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「Ganoderma tsugae」の詳細全文を読む スポンサード リンク
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